Plant Biotechnology

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    Research in our laboratory focuses on the structural studies of plant proteins, peptides and natural products. Major ongoing research activities are, (i) Crystallographic structural studies of plant proteins, especially enzymes involved in plant secondary metabolite pathways (ii) Developing co-crystallization methods to enhance the bio-availability of natural product drug candidates (iii)Structure and folding of synthetic polypeptides containing non-natural amino acids (iv) Mass spectrometric identification and sequencing of biologically active plant peptides in medicinal and aromatic plants (MAPs). Google Scholar Profile:
  • B.Sc. Chemistry
  • M.Sc. Organic Chemistry
  • Ph.D. Bio-Crystallography
  • Indian Institute of Science, Bengaluru, - Research Associate (2010- 2011 )
  • CSIR-CIMAP, Lucknow, - Scientist Fellow (2011- 2013 )
  • CSIR-CIMAP, Lucknow, - Senior Scientist (2013- 2018 )
  • CSIR-CIMAP, Lucknow, - Principal Scientist (2018- till date )
  • Verma, M., Trivedi, L., Vasudev, P. G.. Interaction Patterns of Pyrazolopyri-midines with Receptor Proteins. Journal of Chemical Information and Modelling, 63, 8, 2331-2344 2023
  • Prema G Vasudev. Complete List of Publications.; 2023
  • Thakur, S., Vasudev, P. G.. MYB transcription factors and their role in Medicinal plants. Mol. Biol. Rep. 49, 10995–11008 2022
  • Debnath, S., Ghosh, S., Kumar, D., Vasudev, P.G., Satpati,P., Chatterjee, S.. Effect of Differential Backbone Di-substitution of Gamma Amino Acid Residues on the Conformation and Assembly of their Fmoc Derivatives in Solid and Solution States. Chem. Asian J. e202200356, pp. 1-11 2022
  • Singh, S., Trivedi, L., Vasudev, P. G., Passarella, D., Negi, A. S.. An efficient merging of DBU/enolate and DBU/benzyl bromide organocycles for the synthesis of alpha benzylated 1-indanone derivatives. New J. Chem., 46, pp. 7850-7854 2022
  • Trivedi, L., Gupta, K., Mishra, V., Gopakumar, T. G., Gupta, A., Vasudev, P. G.. Crystal structure and self-assembly on graphite of a Pyrazolo[1,5-c ] pyrimidine derivative. Acta Crystallographica, Section C77, pp. 757-763 2021
  • Agarwal, K., Gupta, K., Sharma, K., Khanka, S., Singh, S., Singh, J., Trivedi, L., Vasudev, P. G., Luqman, S., Khan, F., Singh, D., Gupta, A.. Synthesis and biological evaluation of substituted amide derivatives of C4-ageratochromene dimer analog. Bioorg. Med. Chem. Lett. 50, 128340 2021
  • Gupta, M., Verma, S. K., Singh, S., Trivedi, L., Rout, P. K., Vasudev, P. G., Luqman, S., Darokar, M. P., Bhakuni, R. S., Misra, L.. Anti-proliferative and antibacterial activity of oleo-gum-resin of Boswellia serrata extract and its isolate 3-hydroxy-11-keto-ß-boswellic acid. J. Herbal Medicine, 32, 100546 2021
  • Yadav, S.K., Archana, Singh, R., Singh, P. K., Vasudev, P. G.. Insecticidal protein Tma12 is possibly a lytic polysaccharide monooxygenase. Planta, 249 pp. 1987-1996 2019
  • Kalita, M., Archana, Dimri, A., Vasudev, P. G., Ramapanicker, R.. Synthesis of peptides containing oxo amino acids and their crystallographic analysis. . J Pep Sci., e3148 2019
  • Ahmad, M. I., Dixit, S., Konwar, R., Vasdev, P. G., Yadav, A. K., Tripathi, S., Gupta, M. M., Sharma, A., Gupta, A. . Syntheses of conformationally restricted benzopyran based triarylethylenes as growth inhibitors of carcinoma cells. Bioorganic Med. Chem. Lett. 27, 5040–5045 2017
  • Vasudev, P. G., Aravinda, S., Shamala, N.. Crystal structure of a tripeptide containing aminocyclododecane carboxylic acid: a supramolecular twisted parallel ß-sheet in crystals.. J. Peptide Sci. 22, 166–173 2016
  • Kamal, K., Maurya, H. K., Gupta, A., Vasudev, P. G. . Crystal structures of four delta-keto esters and a Cambridge Structural Database analysis of cyano– halogen interactions.. Acta Crystallogr. C71, 921–928 2015
  • Tiwari, N., Yadav, A. K., Vasudev, P. G., Gupta, M. M. . Isolation and structure determination of furanoeremophilanes from Vitex negundo. . Tetrahedron Lett. 54, 2428-2430. 2013
  • Vasudev, P. G., Banerjee, M., Ramakrishnan, C., Balaram, P.. Asparagine and Glutamine Differ in Their Propensities to Form Specific Side Chain-Backbone Hydrogen Bonded Motifs in Proteins.. Proteins Struct. Funct. Bioinf. 80, 991-1002 2012
  • Kaur, R., Vasudev, P. G., Chattopadhyay, S. K.. 14-deoxyisogarcinol. Acta Crystallogr. E68, o1861-o1862 2012
  • Vasudev, P. G., Chatterjee, S., Shamala, N., Balaram, P. . Structural Chemistry of Peptides Containing Backbone Homologated Amino Acid Residues: Conformational Features of ?, ? and Hybrid Peptides. Chem. Rev. 111, 657-687 2011

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